Jan 14, 2022 · The basic feature of RA is an autoimmune disorder in which autoreactive CD4+ T cells, pathogenic B cells, macrophages, inflammatory cytokines, ...
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Like many autoimmune diseases it is more frequent in women, suggesting a role for sex hormones. Rheumatoid arthritis is characterized by a chronic ...
May 21, 2019 · In rheumatoid arthritis (RA), immune cells mistakenly attack tissues lining the joints. This can lead to stiffness, swelling, pain, and ...
May 6, 2019 · RA is an autoimmune disease with chronic inflammation in the synovium of the joint tissue. This inflammation leads to joint destruction, ...
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Feb 5, 2024 · RA is a complex immune-mediated inflammatory disease, with dysregulation of both innate and adaptive immunity, as well as stromal cells such as ...
Rheumatoid Arthritis (RA) Cellular Disease Models. To aid research and drug discovery for the erosive, autoimmune disease rheumatoid arthritis, ...
Conclusion Our multi-dimensional investigation identified disease relevant T-cell subsets and gene signatures deeply involved in pathogenesis of RA. These ...
Cells that line the joints, producing synovial fluid. In RA, synovial cells express genes and erosive enzymes that contribute to joint degradation. Details ...
Nov 7, 2023 · The findings, published in Nature, shed new light on the variety of cellular causes of RA, which may inform more targeted, effective and patient ...
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